Roger S. Mitchell Lecture. Rheumatoid Lung Disease

Roger s. Mitchell lecture. Chronic obstructive pulmonary disease phenotypes and their clinical relevance.

Phenotype is defined as the outward physical manifestation of patients with chronic obstructive pulmonary disease (COPD); anything that is part of their observable structure, function, or behavior. As such, for patients with COPD, the time has come to move from a disease expressed solely by the degree of airflow limitation, to a much broader and resourceful characterization of COPD. Recent adva...

Rheumatoid arthritis-associated lung disease.

Introduction Rheumatoid arthritis is a systemic inflammatory disorder that most commonly affects the joints, causing progressive, symmetric, erosive destruction of cartilage and bone, which is usually associated with autoantibody production. Rheumatoid arthritis affects ∼1% of the population in developed countries. The incidence and prevalence of rheumatoid arthritis in developing countries is ...

Pyopneumothorax Complicating Rheumatoid Lung Disease.

Specific lung changes occur in association with rheumatoid arthritis but rheumatoid lung nodules unassociated with pneumoconiosis are rare and there are very few reports of cavitation occurring in such nodules (Sieniewicz, Martin, Moore, and Miller, 1962; Noonan, Taylor, and Engleman, 1963; Dumas, Gregory, and Ozer, 1963; Locke, 1963; Yates, 1963). This paper describes another patient in whom r...

Rheumatoid Arthritis Interstitial Lung Disease

Lung disease in rheumatoid arthritis.

Rheumatoid arthritis (RA) affects approximately 1% of the US population frequently has extra-articular manifestations. Most compartments of the lung are susceptible to disease. Interstitial lung disease (ILD) and airways disease are the most common forms of RA-related lung disease. RA-ILD carries the worst prognosis and most often manifests in a histologic pattern of usual interstitial pneumoni...